Cargando…

Metabolomic screening of pre-diagnostic serum samples identifies association between α- and γ-tocopherols and glioblastoma risk

Glioblastoma is associated with poor prognosis with a median survival of one year. High doses of ionizing radiation is the only established exogenous risk factor. To explore new potential biological risk factors for glioblastoma, we investigated alterations in metabolite concentrations in pre-diagno...

Descripción completa

Detalles Bibliográficos
Autores principales:	Björkblom, Benny, Wibom, Carl, Jonsson, Pär, Mörén, Lina, Andersson, Ulrika, Johannesen, Tom Børge, Langseth, Hilde, Antti, Henrik, Melin, Beatrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095057/ https://www.ncbi.nlm.nih.gov/pubmed/27175595 http://dx.doi.org/10.18632/oncotarget.9242

Ejemplares similares

Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study
por: Späth, Florentin, et al.
Publicado: (2016)

Identification of Pre-Diagnostic Metabolic Patterns for Glioma Using Subset Analysis of Matched Repeated Time Points
por: Jonsson, Pär, et al.
Publicado: (2020)

Distinct metabolic hallmarks of WHO classified adult glioma subtypes
por: Björkblom, Benny, et al.
Publicado: (2022)

Low-grade glioma risk SNP rs11706832 is associated with type I interferon response pathway genes in cell lines
por: Rosenbaum, Adam, et al.
Publicado: (2023)

Prediagnostic biomarkers for early detection of glioma—using case–control studies from cohorts as study approach
por: Wu, Wendy Yi-Ying, et al.
Publicado: (2022)

Characterization of the serum metabolome following radiation treatment in patients with high-grade gliomas
por: Mörén, Lina, et al.
Publicado: (2016)

Pre‐diagnostic levels of sVEGFR2, sTNFR2, sIL‐2Rα and sIL‐6R are associated with glioma risk: A nested case–control study of repeated samples
por: Wu, Wendy Yi‐Ying, et al.
Publicado: (2022)

Metabolic response patterns in brain microdialysis fluids and serum during interstitial cisplatin treatment of high-grade glioma
por: Björkblom, Benny, et al.
Publicado: (2019)

Relation between Established Glioma Risk Variants and DNA Methylation in the Tumor
por: Dahlin, Anna M., et al.
Publicado: (2016)

Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma
por: Ghasimi, Soma, et al.
Publicado: (2016)

Altered plasma metabolite levels can be detected years before a glioma diagnosis
por: Löding, Sebastian, et al.
Publicado: (2023)

Metabolomic Screening of Tumor Tissue and Serum in Glioma Patients Reveals Diagnostic and Prognostic Information
por: Mörén, Lina, et al.
Publicado: (2015)

Metabolomic profiling identifies distinct phenotypes for ASS1 positive and negative GBM
por: Mörén, Lina, et al.
Publicado: (2018)

Correction to: Metabolomic profiling identifies distinct phenotypes for ASS1 positive and negative GBM
por: Mörén, Lina, et al.
Publicado: (2018)

CCND2, CTNNB1, DDX3X, GLI2, SMARCA4, MYC, MYCN, PTCH1, TP53, and MLL2 gene variants and risk of childhood medulloblastoma
por: Dahlin, Anna M., et al.
Publicado: (2015)

Genetic variations in VEGF and VEGFR2 and glioblastoma outcome
por: Sjöström, S., et al.
Publicado: (2010)

Associations of Serum Retinol, α-Tocopherol, and γ-Tocopherol with Biomarkers among Healthy Japanese Men
por: Zou, Yu, et al.
Publicado: (2014)

Constrained randomization and multivariate effect projections improve information extraction and biomarker pattern discovery in metabolomics studies involving dependent samples
por: Jonsson, Pär, et al.
Publicado: (2015)

Genetic variation of γ-tocopherol methyltransferase gene contributes to elevated α-tocopherol content in soybean seeds
por: Dwiyanti, Maria S, et al.
Publicado: (2011)

Genetic variations in EGF and EGFR and glioblastoma outcome
por: Sjöström, Sara, et al.
Publicado: (2010)

Engineering of a functional γ-tocopherol transfer protein
por: Aeschimann, Walter, et al.
Publicado: (2020)

Validated and Predictive Processing of Gas Chromatography-Mass Spectrometry Based Metabolomics Data for Large Scale Screening Studies, Diagnostics and Metabolite Pattern Verification
por: Thysell, Elin, et al.
Publicado: (2012)

Novel tocopherol derivatives. Part 32: On the bromination of pyrano[3,2-f]chromenes related to γ-tocopherol
por: Böhmdorfer, Stefan, et al.
Publicado: (2011)

Blood α-Tocopherol, γ-Tocopherol Levels and Risk of Prostate Cancer: A Meta-Analysis of Prospective Studies
por: Cui, Ran, et al.
Publicado: (2014)

The vitamin E isoforms α-tocopherol and γ-tocopherol have opposite associations with spirometric parameters: the CARDIA study
por: Marchese, Michelle E, et al.
Publicado: (2014)

Serum Metabolomic Biomarkers of Dementia
por: Mousavi, Malahat, et al.
Publicado: (2014)

EGFR Gene Variants Are Associated with Specific Somatic Aberrations in Glioma
por: Wibom, Carl, et al.
Publicado: (2012)

Metabolomic analysis of serum alpha-tocopherol among men in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study
por: Lawrence, Wayne R., et al.
Publicado: (2022)

Inhibitory Effect of a γ-Tocopherol-Rich Mixture of Tocopherols on the Formation and Growth of LNCaP Prostate Tumors in Immunodeficient Mice
por: Zheng, Xi, et al.
Publicado: (2011)

Effectiveness of α-, γ- and δ-Tocopherol in a CLA-Rich Oil
por: Márquez-Ruiz, Gloria, et al.
Publicado: (2014)

Genetic Analysis of Reduced γ-Tocopherol Content in Ethiopian Mustard Seeds
por: García-Navarro, Elena, et al.
Publicado: (2016)

Association of Serum γ-Tocopherol Levels with Mortality: The Multiethnic Cohort Study
por: Chai, Weiwen, et al.
Publicado: (2019)

Serum α-Tocopherol and γ-Tocopherol Concentrations and Prostate Cancer Risk in the PLCO Screening Trial: A Nested Case-Control Study
por: Weinstein, Stephanie J., et al.
Publicado: (2012)

α-Tocopherol transfer protein does not regulate the cellular uptake and intracellular distribution of α- and γ-tocopherols and -tocotrienols in cultured liver cells
por: Irías-Mata, Andrea, et al.
Publicado: (2018)

The Genetic Architecture of Gliomagenesis–Genetic Risk Variants Linked to Specific Molecular Subtypes
por: Wu, Wendy Yi-Ying, et al.
Publicado: (2019)

Association of Circulating Vitamin E (α- and γ-Tocopherol) Levels with Gallstone Disease
por: Waniek, Sabina, et al.
Publicado: (2018)

Alpha-Tocopherol Metabolites (The Vitamin E Metabolome) and Their Interindividual Variability during Supplementation
por: Bartolini, Desirée, et al.
Publicado: (2021)

A Novel Combination of γ-Tocopherol-Rich Mixture of Tocopherols and Ascorbic Acid Restores Fertility in Cases of Tyrosine Nitration-Associated Male Infertility in Mice
por: Scarlata, Eleonora, et al.
Publicado: (2020)

Effect of Overexpression of γ-Tocopherol Methyltransferase on α-Tocopherol and Fatty Acid Accumulation and Tolerance to Salt Stress during Seed Germination in Brassica napus L.
por: Guo, Yuan, et al.
Publicado: (2022)

Chemopreventive Activity of Vitamin E in Breast Cancer: A Focus on γ- and δ-Tocopherol
por: Smolarek, Amanda K., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_fsvklkq2fddkho7p6quc7pk58k