MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma

Pituitary spindle cell oncocytoma (SCO) is an uncommon primary pituitary neoplasm that presents with mass effect on adjacent neurovascular structures, similar to non-hormone-producing pituitary adenomas. To determine the molecular etiology of SCO, we performed exome sequencing on four SCO cases, wit...

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Detalles Bibliográficos
Autores principales: Miller, Michael B., Bi, Wenya Linda, Ramkissoon, Lori A., Kang, Yun Jee, Abedalthagafi, Malak, Knoff, David S., Agarwalla, Pankaj K., Wen, Patrick Y., Reardon, David A., Alexander, Brian M., Laws, Edward R., Dunn, Ian F., Beroukhim, Rameen, Ligon, Keith L., Ramkissoon, Shakti H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095058/
https://www.ncbi.nlm.nih.gov/pubmed/27175596
http://dx.doi.org/10.18632/oncotarget.9244

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