Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution

Copper-ionophores that elevate intracellular bioavailable copper display significant therapeutic utility against prostate cancer cells in vitro and in TRAMP (Transgenic Adenocarcinoma of Mouse Prostate) mice. However, the pharmacological basis for their anticancer activity remains unclear, despite i...

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Detalles Bibliográficos
Autores principales: Denoyer, Delphine, Pearson, Helen B., Clatworthy, Sharnel A.S., Smith, Zoe M., Francis, Paul S., Llanos, Roxana M., Volitakis, Irene, Phillips, Wayne A., Meggyesy, Peter M., Masaldan, Shashank, Cater, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095059/
https://www.ncbi.nlm.nih.gov/pubmed/27175597
http://dx.doi.org/10.18632/oncotarget.9245

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