Mouse double minute 2 (MDM2) upregulates Snail expression and induces epithelial-to-mesenchymal transition in breast cancer cells in vitro and in vivo

The oncogene, mouse double minute 2 (MDM2), has been implicated in the pathogenesis of numerous cancers. In this study, we investigated the role of MDM2 in epithelial-to-mesenchymal transition (EMT) and the underlying mechanisms in breast cancer cells in vitro and in vivo. The results showed that up...

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Detalles Bibliográficos
Autores principales: Lu, Xiangdong, Yan, Caiyun, Huang, Yi, Shi, Dongmin, Fu, Ziyi, Qiu, Jinrong, Yin, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095067/
https://www.ncbi.nlm.nih.gov/pubmed/27184007
http://dx.doi.org/10.18632/oncotarget.9287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095067/
https://www.ncbi.nlm.nih.gov/pubmed/27184007
http://dx.doi.org/10.18632/oncotarget.9287

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