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Mouse double minute 2 (MDM2) upregulates Snail expression and induces epithelial-to-mesenchymal transition in breast cancer cells in vitro and in vivo
The oncogene, mouse double minute 2 (MDM2), has been implicated in the pathogenesis of numerous cancers. In this study, we investigated the role of MDM2 in epithelial-to-mesenchymal transition (EMT) and the underlying mechanisms in breast cancer cells in vitro and in vivo. The results showed that up...
Autores principales: | Lu, Xiangdong, Yan, Caiyun, Huang, Yi, Shi, Dongmin, Fu, Ziyi, Qiu, Jinrong, Yin, Yongmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095067/ https://www.ncbi.nlm.nih.gov/pubmed/27184007 http://dx.doi.org/10.18632/oncotarget.9287 |
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