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GADD45β induction by S-adenosylmethionine inhibits hepatocellular carcinoma cell proliferation during acute ischemia-hypoxia
Growth arrest DNA damage-inducible gene 45β (GADD45β), which influences cell growth, apoptosis and cellular response to DNA damage, is downregulated in hepatocellular carcinoma (HCC). S-adenosylmethionine (SAMe) serves as an essential methyl donor in multiple metabolic pathways and is a polyamine an...
Autores principales: | Ma, Ding, Shen, Baiyong, Seewoo, Varun, Tong, Hui, Yang, Weiping, Cheng, Xi, Jin, Zhijian, Peng, Chenghong, Qiu, Weihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095070/ https://www.ncbi.nlm.nih.gov/pubmed/27177086 http://dx.doi.org/10.18632/oncotarget.9295 |
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