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The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer

The stability and integrity of the human genome are maintained by the DNA damage repair (DDR) system. Unrepaired DNA damage is a major source of potentially mutagenic lesions that drive carcinogenesis. In addition to gene mutation, DNA methylation occurs more frequently in DDR genes in human cancer....

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Detalles Bibliográficos
Autores principales:	Gao, Dan, Herman, James G., Guo, Mingzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095080/ https://www.ncbi.nlm.nih.gov/pubmed/26967246 http://dx.doi.org/10.18632/oncotarget.7949

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