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Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis
PURPOSE: The sonic hedgehog (SHH) signalling pathway plays the important role in medulloblastoma (MB). Altered GLI expression plays a key role in these processes, and the inhibition of GLI may be a good cancer-targeted therapy. This study aimed to investigate whether GANT61, a GLI inhibitor, may inh...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095157/ https://www.ncbi.nlm.nih.gov/pubmed/27601167 http://dx.doi.org/10.1007/s00432-016-2241-1 |