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The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation

Cross-linkage of the high-affinity immunoglobulin E (IgE) receptor (FcɛRI) on mast cells by antigen ligation has a critical role in the pathology of IgE-dependent allergic disorders, such as anaphylaxis and asthma. Restraint of intracellular signal transduction pathways that promote release of mast...

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Detalles Bibliográficos
Autores principales:	Yip, Kwok Ho, Kolesnikoff, Natasha, Hauschild, Nicholas, Biggs, Lisa, Lopez, Angel F., Galli, Stephen J., Kumar, Sharad, Grimbaldeston, Michele A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095291/ https://www.ncbi.nlm.nih.gov/pubmed/27786273 http://dx.doi.org/10.1038/ncomms13198

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