Cargando…

Comparison of preventive effect of sildenafil and therapeutic effect of sildenafil treatment in rats with monocrotaline-induced pulmonary arterial hypertension

This study aimed to investigate the potential effects of sildenafil on pulmonary hypertension (PH) in the monocrotaline (MCT)-induced PH rat. Twenty-four, 12-week-old, male Sprague-Dawley rats were injected with MCT or saline solution. After injection of MCT, rats received oral sildenafil immediatel...

Descripción completa

Detalles Bibliográficos
Autores principales:	YOSHIYUKI, Rieko, FUKUSHIMA, Ryuji, TANAKA, Ryo, MACHIDA, Noboru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Veterinary Science 2016
Materias:	Internal Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095631/ https://www.ncbi.nlm.nih.gov/pubmed/27320637 http://dx.doi.org/10.1292/jvms.15-0544

Ejemplares similares

Preventive effect of sildenafil on right ventricular function in rats with monocrotaline-induced pulmonary arterial hypertension
por: Yoshiyuki, Rieko, et al.
Publicado: (2016)

Effects of Single Drug and Combined Short-term Administration of Sildenafil, Pimobendan, and Nicorandil on Right Ventricular Function in Rats With Monocrotaline-induced Pulmonary Hypertension
por: Nakata, Telma M., et al.
Publicado: (2015)

Simvastatin, Sildenafil and Their Combination in Monocrotaline Induced Pulmonary Arterial Hypertension
por: Lee, Dong Seok, et al.
Publicado: (2010)

Dapagliflozin, sildenafil and their combination in monocrotaline-induced pulmonary arterial hypertension
por: Tang, Yi, et al.
Publicado: (2022)

Sildenafil in pediatric pulmonary arterial hypertension
por: Dhariwal, AK, et al.
Publicado: (2015)

Reversible Acute Kidney Injury Associated with Sildenafil Overdose
por: Liu, Baoqiong, et al.
Publicado: (2018)

Sildenafil in the treatment of pulmonary hypertension
por: Barnett, Christopher F, et al.
Publicado: (2006)

Pharmacokinetic and Pharmacodynamic Comparison of Sildenafil‐Bosentan and Sildenafil‐Ambrisentan Combination Therapies for Pulmonary Hypertension
por: Hakamata, A, et al.
Publicado: (2016)

Combination use of sildenafil and simvastatin increases BMPR-II signal transduction in rats with monocrotaline-mediated pulmonary hypertension
por: Kuang, Tuguang, et al.
Publicado: (2011)

Long-term effect of sildenafil on echocardiographic parameters in dogs with asymptomatic myxomatous mitral valve degeneration
por: KIJTAWORNRAT, Anusak, et al.
Publicado: (2017)

Is Sildenafil an Effective Therapy in the Management of Persistent Pulmonary Hypertension?
por: Yaseen, Hakam, et al.
Publicado: (2012)

Update on the clinical utility of sildenafil in the treatment of pulmonary arterial hypertension
por: Ramani, Gautam V, et al.
Publicado: (2010)

Economic evaluation of sildenafil for the treatment of pulmonary arterial hypertension in Indonesia
por: Lilyasari, Oktavia, et al.
Publicado: (2019)

The hypertensive effect of sorafenib is abolished by sildenafil
por: Dabiré, Hubert, et al.
Publicado: (2020)

Sildenafil improves heart rate variability in dogs with asymptomatic myxomatous mitral valve degeneration
por: PIRINTR, Prapawadee, et al.
Publicado: (2017)

Pulmonary arterial size and response to sildenafil in chronic thromboembolic pulmonary hypertension
por: Toshner, Mark R., et al.
Publicado: (2010)

Reported Sildenafil Side Effects in Pediatric Pulmonary Hypertension Patients
por: Siehr, Stephanie L., et al.
Publicado: (2015)

A Comparison of Nifedipine Versus a Combination of Nifedipine and Sildenafil Citrate in the Management of Preterm Labour
por: Hassan, Amber, et al.
Publicado: (2023)

Efficacy, safety and tolerability of bosentan as an adjuvant to sildenafil and sildenafil alone in persistant pulmonary hypertension of newborn (PPHN)
por: Vijay Kumar, J.R., et al.
Publicado: (2021)

The effect of sildenafil on right ventricular remodeling in a rat model of monocrotaline-induced right ventricular failure
por: Bae, Hyun Kyung, et al.
Publicado: (2016)

Current practices in the use of sildenafil for pulmonary arterial hypertension in Brazilian hospitals
por: de Souza, Ana HA, et al.
Publicado: (2009)

Safety and tolerability considerations in the use of sildenafil for children with pulmonary arterial hypertension
por: Dodgen, Andrew L, et al.
Publicado: (2015)

Efficacy of Sildenafil in Patients with Severe COVID-19 and Pulmonary Arterial Hypertension
por: Oliynyk, Oleksandr Valentynovych, et al.
Publicado: (2023)

Bosentan and sildenafil in the treatment of HIV-associated pulmonary hypertension
por: Chinello, Pierangelo, et al.
Publicado: (2011)

Sildenafil in endotoxin-induced pulmonary hypertension: an experimental study
por: Kemper, Daniella Aparecida Godoi, et al.
Publicado: (2021)

Effects of oral sildenafil on exercise capacity in children with pulmonary arterial hypertension: a randomised trial
por: Russell, Stuart, et al.
Publicado: (2019)

Lower Doses of Bosentan in Combination With Sildenafil Might be Beneficial in Pulmonary Arterial Hypertension
por: Amin, Ahmad, et al.
Publicado: (2015)

Population pharmacokinetic analysis of sildenafil in term and preterm infants with pulmonary arterial hypertension
por: Rhee, Su-jin, et al.
Publicado: (2022)

Why sildenafil and sildenafil citrate monohydrate crystals are not stable?
por: Sawatdee, Somchai, et al.
Publicado: (2015)

Clinical deterioration after sildenafil cessation in patients with pulmonary hypertension
por: Keogh, Anne M, et al.
Publicado: (2008)

Sildenafil for bronchopulmonary dysplasia and pulmonary hypertension: a meta-analysis
por: van der Graaf, Marisa, et al.
Publicado: (2019)

Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond
por: Ghofrani, Hossein A., et al.
Publicado: (2006)

Intravenous sildenafil for treatment of early pulmonary hypertension in preterm infants
por: Schroeder, Lukas, et al.
Publicado: (2023)

Efficacy of Sildenafil in Infants with Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension
por: Dillon, Kacie, et al.
Publicado: (2023)

Effect of preoperative oral sildenafil on severe pulmonary artery hypertension in patients undergoing mitral valve replacement
por: Gandhi, Hemang, et al.
Publicado: (2014)

Notopterol Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rat
por: Huang, Lin, et al.
Publicado: (2022)

Is Sildenafil a Therapeutic Option for Noncompaction?
por: Finsterer, Josef, et al.
Publicado: (2014)

Myocardial Impact of NHE1 Regulation by Sildenafil
por: Escudero, Daiana S., et al.
Publicado: (2021)

Epidemiological and clinical features of the endomyocardial form of restrictive cardiomyopathy in cats: a review of 41 cases
por: KIMURA, Yusuke, et al.
Publicado: (2016)

Intravenous sildenafil for postoperative pulmonary hypertension in children with congenital heart disease
por: Fraisse, Alain, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_epefp63rbuo9hi445kvl1472k5