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microRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1β-induced Osteoarthritis

Osteoarthritis is a serious disease of articular cartilage. The pathogenic factors contributing to this disorder are inflammation, extracellular matrix degradation and failure to rebuild the articular cartilage. Preclinical studies suggest that microRNA-140 may play a protective role in osteoarthrit...

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Detalles Bibliográficos
Autores principales: Karlsen, Tommy A, de Souza, Gustavo Antonio, Ødegaard, Bjørn, Engebretsen, Lars, Brinchmann, Jan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095680/
https://www.ncbi.nlm.nih.gov/pubmed/27727249
http://dx.doi.org/10.1038/mtna.2016.64

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