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microRNA-140 Inhibits Inflammation and Stimulates Chondrogenesis in a Model of Interleukin 1β-induced Osteoarthritis
Osteoarthritis is a serious disease of articular cartilage. The pathogenic factors contributing to this disorder are inflammation, extracellular matrix degradation and failure to rebuild the articular cartilage. Preclinical studies suggest that microRNA-140 may play a protective role in osteoarthrit...
Autores principales: | Karlsen, Tommy A, de Souza, Gustavo Antonio, Ødegaard, Bjørn, Engebretsen, Lars, Brinchmann, Jan E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095680/ https://www.ncbi.nlm.nih.gov/pubmed/27727249 http://dx.doi.org/10.1038/mtna.2016.64 |
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