Cargando…

FANCM c.5101C>T mutation associates with breast cancer survival and treatment outcome

Breast cancer (BC) is a heterogeneous disease, and different tumor characteristics and genetic variation may affect the clinical outcome. The FANCM c.5101C > T nonsense mutation in the Finnish population associates with increased risk of breast cancer, especially for triple‐negative breast cancer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kiiski, Johanna I., Fagerholm, Rainer, Tervasmäki, Anna, Pelttari, Liisa M., Khan, Sofia, Jamshidi, Maral, Mantere, Tuomo, Pylkäs, Katri, Bartek, Jiri, Bartkova, Jirina, Mannermaa, Arto, Tengström, Maria, Kosma, Veli‐Matti, Winqvist, Robert, Kallioniemi, Anne, Aittomäki, Kristiina, Blomqvist, Carl, Nevanlinna, Heli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Cancer Genetics and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095781/ https://www.ncbi.nlm.nih.gov/pubmed/27542569 http://dx.doi.org/10.1002/ijc.30394

Ejemplares similares

FANCM mutation c.5791C>T is a risk factor for triple-negative breast cancer in the Finnish population
por: Kiiski, Johanna I., et al.
Publicado: (2017)

Machine learning identifies interacting genetic variants contributing to breast cancer risk: A case study in Finnish cases and controls
por: Behravan, Hamid, et al.
Publicado: (2018)

Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility
por: Mantere, Tuomo, et al.
Publicado: (2017)

Targeted Next-Generation Sequencing Identifies a Recurrent Mutation in MCPH1 Associating with Hereditary Breast Cancer Susceptibility
por: Mantere, Tuomo, et al.
Publicado: (2016)

SULT1A1 rs9282861 polymorphism-a potential modifier of efficacy of the systemic adjuvant therapy in breast cancer?
por: Tengström, Maria, et al.
Publicado: (2012)

Predicting breast cancer risk using interacting genetic and demographic factors and machine learning
por: Behravan, Hamid, et al.
Publicado: (2020)

RAD51, XRCC3, and XRCC2 mutation screening in Finnish breast cancer families
por: Pelttari, Liisa M, et al.
Publicado: (2015)

Evaluating the role of NTHL1 p.Q90* allele in inherited breast cancer predisposition
por: Kumpula, Timo, et al.
Publicado: (2020)

High Cell-Free DNA Integrity Is Associated with Poor Breast Cancer Survival
por: Lamminaho, Maria, et al.
Publicado: (2021)

Recurrent CYP2C19 deletion allele is associated with triple-negative breast cancer
por: Tervasmäki, Anna, et al.
Publicado: (2014)

Truncating TINF2 p.Tyr312Ter variant and inherited breast cancer susceptibility
por: Koivuluoma, Susanna, et al.
Publicado: (2022)

High mutation burden of circulating cell‐free DNA in early‐stage breast cancer patients is associated with a poor relapse‐free survival
por: Kujala, Jouni, et al.
Publicado: (2020)

The debatable presence of PIWI‐interacting RNAs in invasive breast cancer
por: Kärkkäinen, Emmi, et al.
Publicado: (2021)

Expression profiles of small non-coding RNAs in breast cancer tumors characterize clinicopathological features and show prognostic and predictive potential
por: Kärkkäinen, Emmi, et al.
Publicado: (2022)

Recurrent moderate‐risk mutations in Finnish breast and ovarian cancer patients
por: Nurmi, Anna, et al.
Publicado: (2019)

Tumor suppressor MCPH1 regulates gene expression profiles related to malignant conversion and chromosomal assembly
por: Tervasmäki, Anna, et al.
Publicado: (2019)

Circulating Cell-Free DNA Reflects the Clonal Evolution of Breast Cancer Tumors
por: Kujala, Jouni, et al.
Publicado: (2022)

Type II Transmembrane Serine Protease Gene Variants Associate with Breast Cancer
por: Luostari, Kaisa, et al.
Publicado: (2014)

Histone demethylase GASC1 - a potential prognostic and predictive marker in invasive breast cancer
por: Berdel, Bozena, et al.
Publicado: (2012)

Polygenic risk score is associated with increased disease risk in 52 Finnish breast cancer families
por: Muranen, Taru A., et al.
Publicado: (2016)

Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival
por: Pelkonen, Mikko, et al.
Publicado: (2015)

Overexpression of MicroRNA-200c Predicts Poor Outcome in Patients with PR-Negative Breast Cancer
por: Tuomarila, Marie, et al.
Publicado: (2014)

CHEK2 c.1100delC mutation is associated with an increased risk for male breast cancer in Finnish patient population
por: Hallamies, Sanna, et al.
Publicado: (2017)

NTHL1 is a recessive cancer susceptibility gene
por: Nurmi, Anna K., et al.
Publicado: (2023)

MiR-34a Expression Has an Effect for Lower Risk of Metastasis and Associates with Expression Patterns Predicting Clinical Outcome in Breast Cancer
por: Peurala, Hanna, et al.
Publicado: (2011)

Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications
por: Muranen, Taru A, et al.
Publicado: (2011)

Nuclei instance segmentation from histopathology images using Bayesian dropout based deep learning
por: Gudhe, Naga Raju, et al.
Publicado: (2023)

Evaluating the role of CHEK2 p.(Asp438Tyr) allele in inherited breast cancer predisposition
por: Kumpula, Timo A., et al.
Publicado: (2023)

Exome sequencing identified rare recurrent copy number variants and hereditary breast cancer susceptibility
por: Kumpula, Timo A., et al.
Publicado: (2023)

ATM c.7570G>C is a high‐risk allele for breast cancer
por: Kankuri‐Tammilehto, Minna, et al.
Publicado: (2022)

Variants on the promoter region of PTEN affect breast cancer progression and patient survival
por: Heikkinen, Tuomas, et al.
Publicado: (2011)

Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer
por: Khan, Sofia, et al.
Publicado: (2017)

In Vitro and In Vivo Survival and Colonic Adhesion of Pediococcus acidilactici MTCC5101 in Human Gut
por: Balgir, Praveen P., et al.
Publicado: (2013)

γ-Secretase Components as Predictors of Breast Cancer Outcome
por: Peltonen, Hanna M., et al.
Publicado: (2013)

ALTernative Functions for Human FANCM at Telomeres
por: Domingues-Silva, Beatriz, et al.
Publicado: (2019)

FANCM c5791C>T stopgain mutation (rs144567652) is a familial colorectal cancer risk factor
por: Cannon‐Albright, Lisa A., et al.
Publicado: (2020)

The Spectrum of FANCM Protein Truncating Variants in European Breast Cancer Cases
por: Figlioli, Gisella, et al.
Publicado: (2020)

High miR-30 Expression Associates with Improved Breast Cancer Patient Survival and Treatment Outcome
por: Jamshidi, Maral, et al.
Publicado: (2021)

Multi-level dilated residual network for biomedical image segmentation
por: Gudhe, Naga Raju, et al.
Publicado: (2021)

Area-based breast percentage density estimation in mammograms using weight-adaptive multitask learning
por: Gudhe, Naga Raju, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gf5jtb5rtgd85a37093lt0ivl6