Crystal structure of olivetolic acid: a natural product from Cetrelia sanguinea (Schaer.)

The title compound, C(12)H(16)O(4) (systematic name: 2,4-dihy­droxy-6-pentyl­benzoic acid) is a natural product isolated from C. sanguinea (Schaer.) and is reported to have various pharmacological activities. The mol­ecule is approximately planar (r.m.s. deviation for the non-H atoms = 0.096 Å) and...

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Autores principales: Ismed, Friardi, Farhan, Aulia, Bakhtiar, Amri, Zaini, Erizal, Nugraha, Yuda Prasetya, Dwichandra Putra, Okky, Uekusa, Hidehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095839/
https://www.ncbi.nlm.nih.gov/pubmed/27840714
http://dx.doi.org/10.1107/S2056989016016273
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author Ismed, Friardi
Farhan, Aulia
Bakhtiar, Amri
Zaini, Erizal
Nugraha, Yuda Prasetya
Dwichandra Putra, Okky
Uekusa, Hidehiro
author_facet Ismed, Friardi
Farhan, Aulia
Bakhtiar, Amri
Zaini, Erizal
Nugraha, Yuda Prasetya
Dwichandra Putra, Okky
Uekusa, Hidehiro
author_sort Ismed, Friardi
collection PubMed
description The title compound, C(12)H(16)O(4) (systematic name: 2,4-dihy­droxy-6-pentyl­benzoic acid) is a natural product isolated from C. sanguinea (Schaer.) and is reported to have various pharmacological activities. The mol­ecule is approximately planar (r.m.s. deviation for the non-H atoms = 0.096 Å) and features an intra­molecular O—H⋯O hydrogen bond. In the crystal, each olivetolic acid mol­ecule is connected to three neighbours via O—H⋯O hydrogen bonds, generating (10-1) sheets. This crystal is essentially isostructural with a related resorcinolic acid with a longer alkyl chain.
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spelling pubmed-50958392016-11-11 Crystal structure of olivetolic acid: a natural product from Cetrelia sanguinea (Schaer.) Ismed, Friardi Farhan, Aulia Bakhtiar, Amri Zaini, Erizal Nugraha, Yuda Prasetya Dwichandra Putra, Okky Uekusa, Hidehiro Acta Crystallogr E Crystallogr Commun Research Communications The title compound, C(12)H(16)O(4) (systematic name: 2,4-dihy­droxy-6-pentyl­benzoic acid) is a natural product isolated from C. sanguinea (Schaer.) and is reported to have various pharmacological activities. The mol­ecule is approximately planar (r.m.s. deviation for the non-H atoms = 0.096 Å) and features an intra­molecular O—H⋯O hydrogen bond. In the crystal, each olivetolic acid mol­ecule is connected to three neighbours via O—H⋯O hydrogen bonds, generating (10-1) sheets. This crystal is essentially isostructural with a related resorcinolic acid with a longer alkyl chain. International Union of Crystallography 2016-10-18 /pmc/articles/PMC5095839/ /pubmed/27840714 http://dx.doi.org/10.1107/S2056989016016273 Text en © Ismed et al. 2016 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Research Communications
Ismed, Friardi
Farhan, Aulia
Bakhtiar, Amri
Zaini, Erizal
Nugraha, Yuda Prasetya
Dwichandra Putra, Okky
Uekusa, Hidehiro
Crystal structure of olivetolic acid: a natural product from Cetrelia sanguinea (Schaer.)
title Crystal structure of olivetolic acid: a natural product from Cetrelia sanguinea (Schaer.)
title_full Crystal structure of olivetolic acid: a natural product from Cetrelia sanguinea (Schaer.)
title_fullStr Crystal structure of olivetolic acid: a natural product from Cetrelia sanguinea (Schaer.)
title_full_unstemmed Crystal structure of olivetolic acid: a natural product from Cetrelia sanguinea (Schaer.)
title_short Crystal structure of olivetolic acid: a natural product from Cetrelia sanguinea (Schaer.)
title_sort crystal structure of olivetolic acid: a natural product from cetrelia sanguinea (schaer.)
topic Research Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095839/
https://www.ncbi.nlm.nih.gov/pubmed/27840714
http://dx.doi.org/10.1107/S2056989016016273
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