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Crystal structures of 2′-benzoyl-1′-(4-methylphenyl)-1,1′,2,2′,5′,6′,7′,7a′-octahydrospiro[indole-3,3′-pyrrolizin]-2-one and 2′-(4-bromobenzoyl)-1′-(2-chlorophenyl)-1,1′,2,2′,5′,6′,7′,7a′-octahydrospiro[indole-3,3′-pyrrolizin]-2-one
The two title compounds, C(28)H(26)N(2)O(2), (I), and C(27)H(22)BrClN(2)O(2), (II), differ in their substituents, viz.4-methylphenyl and benzoyl rings in (I) replaced by 2-chlorophenyl and 4- bromobenzoyl, respectively, in (II). A significant difference between the two molecules is found in the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095850/ https://www.ncbi.nlm.nih.gov/pubmed/27840725 http://dx.doi.org/10.1107/S2056989016016741 |
Sumario: | The two title compounds, C(28)H(26)N(2)O(2), (I), and C(27)H(22)BrClN(2)O(2), (II), differ in their substituents, viz.4-methylphenyl and benzoyl rings in (I) replaced by 2-chlorophenyl and 4- bromobenzoyl, respectively, in (II). A significant difference between the two molecules is found in the deviation of the benzoyl O atom from the least-squares plane of the ring to which it is attached [0.593 (4) and 0.131 (3) Å, respectively], a fact which may be attributed to the different participation of the benzoyl O atoms as acceptors in their intermolecular C—H⋯O interactions. The chemical modifications in (I) and (II) do not seem to affect the type nor strength of the intermolecular N—H⋯N and C—H⋯O hydrogen bonds responsible for the two crystal structures, such that the aggregation of molecules appears similar in spite of the molecular changes. |
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