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The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease
In the 1960s, Christian Anfinsen postulated that the unique three-dimensional structure of a protein is determined by its amino acid sequence. This work laid the foundation for the sequence–structure–function paradigm, which states that the sequence of a protein determines its structure, and structu...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095923/ https://www.ncbi.nlm.nih.gov/pubmed/27911701 http://dx.doi.org/10.1042/BST20160172 |