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Unsupervised gene set testing based on random matrix theory
BACKGROUND: Gene set testing, or pathway analysis, is a bioinformatics technique that performs statistical testing on biologically meaningful sets of genomic variables. Although originally developed for supervised analyses, i.e., to test the association between gene sets and an outcome variable, gen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096314/ https://www.ncbi.nlm.nih.gov/pubmed/27809777 http://dx.doi.org/10.1186/s12859-016-1299-8 |