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Unsupervised gene set testing based on random matrix theory

BACKGROUND: Gene set testing, or pathway analysis, is a bioinformatics technique that performs statistical testing on biologically meaningful sets of genomic variables. Although originally developed for supervised analyses, i.e., to test the association between gene sets and an outcome variable, gen...

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Detalles Bibliográficos
Autores principales: Frost, H. Robert, Amos, Christopher I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096314/
https://www.ncbi.nlm.nih.gov/pubmed/27809777
http://dx.doi.org/10.1186/s12859-016-1299-8

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