Transmission tree of the highly pathogenic avian influenza (H5N1) epidemic in Israel, 2015

The transmission tree of the Israeli 2015 epidemic of highly pathogenic avian influenza (H5N1) was modelled by combining the spatio-temporal distribution of the outbreaks and the genetic distance between virus isolates. The most likely successions of transmission events were determined and transmiss...

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Autores principales: Vergne, Timothée, Fournié, Guillaume, Markovich, Michal Perry, Ypma, Rolf J. F., Katz, Ram, Shkoda, Irena, Lublin, Avishai, Perk, Shimon, Pfeiffer, Dirk U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096331/
https://www.ncbi.nlm.nih.gov/pubmed/27814754
http://dx.doi.org/10.1186/s13567-016-0393-2
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author Vergne, Timothée
Fournié, Guillaume
Markovich, Michal Perry
Ypma, Rolf J. F.
Katz, Ram
Shkoda, Irena
Lublin, Avishai
Perk, Shimon
Pfeiffer, Dirk U.
author_facet Vergne, Timothée
Fournié, Guillaume
Markovich, Michal Perry
Ypma, Rolf J. F.
Katz, Ram
Shkoda, Irena
Lublin, Avishai
Perk, Shimon
Pfeiffer, Dirk U.
author_sort Vergne, Timothée
collection PubMed
description The transmission tree of the Israeli 2015 epidemic of highly pathogenic avian influenza (H5N1) was modelled by combining the spatio-temporal distribution of the outbreaks and the genetic distance between virus isolates. The most likely successions of transmission events were determined and transmission parameters were estimated. It was found that the median infectious pressure exerted at 1 km was 1.59 times (95% CI 1.04, 6.01) and 3.54 times (95% CI 1.09, 131.75) higher than that exerted at 2 and 5 km, respectively, and that three farms were responsible for all seven transmission events. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13567-016-0393-2) contains supplementary material, which is available to authorized users.
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spelling pubmed-50963312016-11-07 Transmission tree of the highly pathogenic avian influenza (H5N1) epidemic in Israel, 2015 Vergne, Timothée Fournié, Guillaume Markovich, Michal Perry Ypma, Rolf J. F. Katz, Ram Shkoda, Irena Lublin, Avishai Perk, Shimon Pfeiffer, Dirk U. Vet Res Short Report The transmission tree of the Israeli 2015 epidemic of highly pathogenic avian influenza (H5N1) was modelled by combining the spatio-temporal distribution of the outbreaks and the genetic distance between virus isolates. The most likely successions of transmission events were determined and transmission parameters were estimated. It was found that the median infectious pressure exerted at 1 km was 1.59 times (95% CI 1.04, 6.01) and 3.54 times (95% CI 1.09, 131.75) higher than that exerted at 2 and 5 km, respectively, and that three farms were responsible for all seven transmission events. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13567-016-0393-2) contains supplementary material, which is available to authorized users. BioMed Central 2016-11-04 2016 /pmc/articles/PMC5096331/ /pubmed/27814754 http://dx.doi.org/10.1186/s13567-016-0393-2 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Report
Vergne, Timothée
Fournié, Guillaume
Markovich, Michal Perry
Ypma, Rolf J. F.
Katz, Ram
Shkoda, Irena
Lublin, Avishai
Perk, Shimon
Pfeiffer, Dirk U.
Transmission tree of the highly pathogenic avian influenza (H5N1) epidemic in Israel, 2015
title Transmission tree of the highly pathogenic avian influenza (H5N1) epidemic in Israel, 2015
title_full Transmission tree of the highly pathogenic avian influenza (H5N1) epidemic in Israel, 2015
title_fullStr Transmission tree of the highly pathogenic avian influenza (H5N1) epidemic in Israel, 2015
title_full_unstemmed Transmission tree of the highly pathogenic avian influenza (H5N1) epidemic in Israel, 2015
title_short Transmission tree of the highly pathogenic avian influenza (H5N1) epidemic in Israel, 2015
title_sort transmission tree of the highly pathogenic avian influenza (h5n1) epidemic in israel, 2015
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096331/
https://www.ncbi.nlm.nih.gov/pubmed/27814754
http://dx.doi.org/10.1186/s13567-016-0393-2
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