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ANTIMICROBIAL SUSCEPTIBILITY OF Streptococcus agalactiae ISOLATED FROM PREGNANT WOMEN

INTRODUCTION: Group B streptococcus (GBS) or Streptococcus agalactiae can colonize the gastrointestinal and genitourinary tracts and has been considered one of the most important risk factors for the development of neonatal disease. The present study evaluated the antimicrobial susceptibility of GBS...

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Autores principales: de MELO, Simone Cristina Castanho Sabaini, SANTOS, Nathally Claudiane de Souza, de OLIVEIRA, Marcia, SCODRO, Regiane Bertin de Lima, CARDOSO, Rosilene Fressatti, PÁDUA, Rúbia Andreia Falleiros, SILVA, Flavia Teixeira Ribeiro, COSTA, Aline Balandis, CARVALHO, Maria Dalva de Barros, PELLOSO, Sandra Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096637/
https://www.ncbi.nlm.nih.gov/pubmed/27828624
http://dx.doi.org/10.1590/S1678-9946201658083
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author de MELO, Simone Cristina Castanho Sabaini
SANTOS, Nathally Claudiane de Souza
de OLIVEIRA, Marcia
SCODRO, Regiane Bertin de Lima
CARDOSO, Rosilene Fressatti
PÁDUA, Rúbia Andreia Falleiros
SILVA, Flavia Teixeira Ribeiro
COSTA, Aline Balandis
CARVALHO, Maria Dalva de Barros
PELLOSO, Sandra Marisa
author_facet de MELO, Simone Cristina Castanho Sabaini
SANTOS, Nathally Claudiane de Souza
de OLIVEIRA, Marcia
SCODRO, Regiane Bertin de Lima
CARDOSO, Rosilene Fressatti
PÁDUA, Rúbia Andreia Falleiros
SILVA, Flavia Teixeira Ribeiro
COSTA, Aline Balandis
CARVALHO, Maria Dalva de Barros
PELLOSO, Sandra Marisa
author_sort de MELO, Simone Cristina Castanho Sabaini
collection PubMed
description INTRODUCTION: Group B streptococcus (GBS) or Streptococcus agalactiae can colonize the gastrointestinal and genitourinary tracts and has been considered one of the most important risk factors for the development of neonatal disease. The present study evaluated the antimicrobial susceptibility of GBS isolates from pregnant women who were attended at a public health service in Northern Paraná, Brazil. METHODS: A descriptive analytical cross-sectional study was performed with 544 pregnant women, at ≥ 35 weeks of gestation. One hundred and thirty-six GBS isolates from pregnant women were tested for antimicrobial susceptibility. RESULTS: All of the GBS isolates showed susceptibility to the drug that is most frequently used for intrapartum prophylaxis: penicillin. Resistance to clindamycin and erythromycin was detected, thus decreasing the options of prophylaxis in women who are allergic to penicillin. CONCLUSIONS: Additional studies should be conducted to increase the knowledge of GBS sensitivity profile to antimicrobials in other health centers.
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spelling pubmed-50966372016-11-14 ANTIMICROBIAL SUSCEPTIBILITY OF Streptococcus agalactiae ISOLATED FROM PREGNANT WOMEN de MELO, Simone Cristina Castanho Sabaini SANTOS, Nathally Claudiane de Souza de OLIVEIRA, Marcia SCODRO, Regiane Bertin de Lima CARDOSO, Rosilene Fressatti PÁDUA, Rúbia Andreia Falleiros SILVA, Flavia Teixeira Ribeiro COSTA, Aline Balandis CARVALHO, Maria Dalva de Barros PELLOSO, Sandra Marisa Rev Inst Med Trop Sao Paulo Original Article INTRODUCTION: Group B streptococcus (GBS) or Streptococcus agalactiae can colonize the gastrointestinal and genitourinary tracts and has been considered one of the most important risk factors for the development of neonatal disease. The present study evaluated the antimicrobial susceptibility of GBS isolates from pregnant women who were attended at a public health service in Northern Paraná, Brazil. METHODS: A descriptive analytical cross-sectional study was performed with 544 pregnant women, at ≥ 35 weeks of gestation. One hundred and thirty-six GBS isolates from pregnant women were tested for antimicrobial susceptibility. RESULTS: All of the GBS isolates showed susceptibility to the drug that is most frequently used for intrapartum prophylaxis: penicillin. Resistance to clindamycin and erythromycin was detected, thus decreasing the options of prophylaxis in women who are allergic to penicillin. CONCLUSIONS: Additional studies should be conducted to increase the knowledge of GBS sensitivity profile to antimicrobials in other health centers. Instituto de Medicina Tropical 2016-11-03 /pmc/articles/PMC5096637/ /pubmed/27828624 http://dx.doi.org/10.1590/S1678-9946201658083 Text en http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
de MELO, Simone Cristina Castanho Sabaini
SANTOS, Nathally Claudiane de Souza
de OLIVEIRA, Marcia
SCODRO, Regiane Bertin de Lima
CARDOSO, Rosilene Fressatti
PÁDUA, Rúbia Andreia Falleiros
SILVA, Flavia Teixeira Ribeiro
COSTA, Aline Balandis
CARVALHO, Maria Dalva de Barros
PELLOSO, Sandra Marisa
ANTIMICROBIAL SUSCEPTIBILITY OF Streptococcus agalactiae ISOLATED FROM PREGNANT WOMEN
title ANTIMICROBIAL SUSCEPTIBILITY OF Streptococcus agalactiae ISOLATED FROM PREGNANT WOMEN
title_full ANTIMICROBIAL SUSCEPTIBILITY OF Streptococcus agalactiae ISOLATED FROM PREGNANT WOMEN
title_fullStr ANTIMICROBIAL SUSCEPTIBILITY OF Streptococcus agalactiae ISOLATED FROM PREGNANT WOMEN
title_full_unstemmed ANTIMICROBIAL SUSCEPTIBILITY OF Streptococcus agalactiae ISOLATED FROM PREGNANT WOMEN
title_short ANTIMICROBIAL SUSCEPTIBILITY OF Streptococcus agalactiae ISOLATED FROM PREGNANT WOMEN
title_sort antimicrobial susceptibility of streptococcus agalactiae isolated from pregnant women
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096637/
https://www.ncbi.nlm.nih.gov/pubmed/27828624
http://dx.doi.org/10.1590/S1678-9946201658083
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