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Chronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult Mice

The transcription factor NF-E2-related factor 2 (Nrf2) induces cytoprotective genes, but has also been linked to the regulation of hepatic energy metabolism. In order to assess the pharmacological potential of hepatic Nrf2 activation in metabolic disease, Nrf2 was activated over 7 weeks in mice on W...

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Detalles Bibliográficos
Autores principales: Brachs, Sebastian, Winkel, Angelika F., Polack, James, Tang, Hui, Brachs, Maria, Margerie, Daniel, Brunner, Bodo, Jahn-Hofmann, Kerstin, Ruetten, Hartmut, Spranger, Joachim, Schmoll, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096693/
https://www.ncbi.nlm.nih.gov/pubmed/27814396
http://dx.doi.org/10.1371/journal.pone.0166110