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Chronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult Mice
The transcription factor NF-E2-related factor 2 (Nrf2) induces cytoprotective genes, but has also been linked to the regulation of hepatic energy metabolism. In order to assess the pharmacological potential of hepatic Nrf2 activation in metabolic disease, Nrf2 was activated over 7 weeks in mice on W...
Autores principales: | Brachs, Sebastian, Winkel, Angelika F., Polack, James, Tang, Hui, Brachs, Maria, Margerie, Daniel, Brunner, Bodo, Jahn-Hofmann, Kerstin, Ruetten, Hartmut, Spranger, Joachim, Schmoll, Dieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096693/ https://www.ncbi.nlm.nih.gov/pubmed/27814396 http://dx.doi.org/10.1371/journal.pone.0166110 |
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