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Ataxia telangiectasia mutated (ATM) interacts with p400 ATPase for an efficient DNA damage response
BACKGROUND: Ataxia telangiectasia mutated (ATM) and TRRAP proteins belong to the phosphatidylinositol 3-kinase-related kinase family and are involved in DNA damage repair and chromatin remodeling. ATM is a checkpoint kinase that is recruited to sites of DNA double-strand breaks where it phosphorylat...
Autores principales: | Smith, Rebecca J., Savoian, Matthew S., Weber, Lauren E., Park, Jeong Hyeon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097431/ https://www.ncbi.nlm.nih.gov/pubmed/27814680 http://dx.doi.org/10.1186/s12867-016-0075-7 |
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