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Targeted in vivo delivery of EGFR siRNA inhibits ovarian cancer growth and enhances drug sensitivity
A functionalized nanohydrogel siRNA delivery system and a mouse model of serous ovarian cancer were used to test predictions from previous cell line studies that knockdown of EGFR (epidermal growth factor receptor) may be of clinical significance in the treatment of epithelial tumors especially with...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098171/ https://www.ncbi.nlm.nih.gov/pubmed/27819259 http://dx.doi.org/10.1038/srep36518 |