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IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection

IL-21 is produced predominantly by activated CD4(+) T cells and has pleiotropic effects on immunity via the IL-21 receptor (IL-21R), a member of the common gamma chain (γ(c)) cytokine receptor family. We show that IL-21 signaling plays a crucial role in T cell responses during Mycobacterium tubercul...

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Detalles Bibliográficos
Autores principales:	Booty, Matthew G., Barreira-Silva, Palmira, Carpenter, Stephen M., Nunes-Alves, Cláudio, Jacques, Miye K., Stowell, Britni L., Jayaraman, Pushpa, Beamer, Gillian, Behar, Samuel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098191/ https://www.ncbi.nlm.nih.gov/pubmed/27819295 http://dx.doi.org/10.1038/srep36720

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