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Efficacy of recombinant human soluble thrombomodulin for the treatment of acute exacerbation of idiopathic pulmonary fibrosis: a single arm, non-randomized prospective clinical trial
BACKGROUND: Coagulation abnormalities are involved in the pathogenesis of acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF). The administration of recombinant human soluble thrombomodulin (rhTM), which has both anti-inflammatory and anticoagulant activities, improves outcomes and respira...
Autores principales: | Hayakawa, Sho, Matsuzawa, Yasuo, Irie, Tamako, Rikitake, Hagino, Okada, Noriaki, Suzuki, Yasuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098285/ https://www.ncbi.nlm.nih.gov/pubmed/27826444 http://dx.doi.org/10.1186/s40248-016-0074-z |
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