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Efficacy of recombinant human soluble thrombomodulin for the treatment of acute exacerbation of idiopathic pulmonary fibrosis: a single arm, non-randomized prospective clinical trial

BACKGROUND: Coagulation abnormalities are involved in the pathogenesis of acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF). The administration of recombinant human soluble thrombomodulin (rhTM), which has both anti-inflammatory and anticoagulant activities, improves outcomes and respira...

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Detalles Bibliográficos
Autores principales: Hayakawa, Sho, Matsuzawa, Yasuo, Irie, Tamako, Rikitake, Hagino, Okada, Noriaki, Suzuki, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098285/
https://www.ncbi.nlm.nih.gov/pubmed/27826444
http://dx.doi.org/10.1186/s40248-016-0074-z

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