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Amyloid misfolding, aggregation, and the early onset of protein deposition diseases: insights from AFM experiments and computational analyses
The development of Alzheimer’s disease is believed to be caused by the assembly of amyloid β proteins into aggregates and the formation of extracellular senile plaques. Similar models suggest that structural misfolding and aggregation of proteins are associated with the early onset of diseases such...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098429/ https://www.ncbi.nlm.nih.gov/pubmed/27830177 http://dx.doi.org/10.3934/molsci.2015.3.190 |