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CCL2/CCR2 Regulates the Tumor Microenvironment in HER-2/neu-Driven Mammary Carcinomas in Mice
Chronic inflammation is a hallmark of cancer. Inflammatory chemokines, such as C-C chemokine ligand 2 (CCL2), are often present in tumors but their roles in cancer initiation and maintenance are not clear. Here we report that CCL2 promotes mammary carcinoma development in a clinically relevant murin...
Autores principales: | Chen, Xuguang, Wang, Yunyue, Nelson, David, Tian, Sara, Mulvey, Erin, Patel, Bhumi, Conti, Ilaria, Jaen, Juan, Rollins, Barrett J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098736/ https://www.ncbi.nlm.nih.gov/pubmed/27820834 http://dx.doi.org/10.1371/journal.pone.0165595 |
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