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CCL2/CCR2 Regulates the Tumor Microenvironment in HER-2/neu-Driven Mammary Carcinomas in Mice

Chronic inflammation is a hallmark of cancer. Inflammatory chemokines, such as C-C chemokine ligand 2 (CCL2), are often present in tumors but their roles in cancer initiation and maintenance are not clear. Here we report that CCL2 promotes mammary carcinoma development in a clinically relevant murin...

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Detalles Bibliográficos
Autores principales: Chen, Xuguang, Wang, Yunyue, Nelson, David, Tian, Sara, Mulvey, Erin, Patel, Bhumi, Conti, Ilaria, Jaen, Juan, Rollins, Barrett J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098736/
https://www.ncbi.nlm.nih.gov/pubmed/27820834
http://dx.doi.org/10.1371/journal.pone.0165595

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