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Inoculated Cell Density as a Determinant Factor of the Growth Dynamics and Metastatic Efficiency of a Breast Cancer Murine Model
4T1 metastatic breast cancer model have been widely used to study stage IV human breast cancer. However, the frequent inoculation of a large number of cells, gives rise to fast growing tumors, as well as to a surprisingly low metastatic take rate. The present work aimed at establishing the condition...
Autores principales: | Gregório, Ana C., Fonseca, Nuno A., Moura, Vera, Lacerda, Manuela, Figueiredo, Paulo, Simões, Sérgio, Dias, Sérgio, Moreira, João Nuno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098815/ https://www.ncbi.nlm.nih.gov/pubmed/27820870 http://dx.doi.org/10.1371/journal.pone.0165817 |
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