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Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice

Neurons innervating the airways contribute to airway hyperreactivity (AHR), a hallmark feature of asthma. Several observations suggested that acid-sensing ion channels (ASICs), neuronal cation channels activated by protons, might contribute to AHR. For example, ASICs are found in vagal sensory neuro...

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Detalles Bibliográficos
Autores principales:	Reznikov, Leah R., Meyerholz, David K., Adam, Ryan J., Abou Alaiwa, Mahmoud, Jaffer, Omar, Michalski, Andrew S., Powers, Linda S., Price, Margaret P., Stoltz, David A., Welsh, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098826/ https://www.ncbi.nlm.nih.gov/pubmed/27820848 http://dx.doi.org/10.1371/journal.pone.0166089

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