Cargando…
Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses
Neuroligins (NLGNs) are postsynaptic cell adhesion molecules that interact trans-synaptically with neurexins to mediate synapse development and function. NLGN2 is only at inhibitory synapses while NLGN3 is at both excitatory and inhibitory synapses. We found that NLGN3 function at inhibitory synapse...
Autores principales: | Nguyen, Quynh-Anh, Horn, Meryl E, Nicoll, Roger A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098909/ https://www.ncbi.nlm.nih.gov/pubmed/27805570 http://dx.doi.org/10.7554/eLife.19236 |
Ejemplares similares
-
An Autism-Associated Neuroligin-3 Mutation Affects Developmental Synapse Elimination in the Cerebellum
por: Lai, Esther Suk King, et al.
Publicado: (2021) -
Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development
por: Pettem, Katherine L., et al.
Publicado: (2013) -
Breaking down to build up: Neuroligin’s C-terminal domain strengthens the synapse
por: Newell-Litwa, Karen A.
Publicado: (2016) -
Neuroligin-3 confines AMPA receptors into nanoclusters, thereby controlling synaptic strength at the calyx of Held synapses
por: Han, Ying, et al.
Publicado: (2022) -
Neuroligin-3: A Circuit-Specific Synapse Organizer That Shapes Normal Function and Autism Spectrum Disorder-Associated Dysfunction
por: Uchigashima, Motokazu, et al.
Publicado: (2021)