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Multiparameter Evaluation of the Heterogeneity of Circulating Tumor Cells Using Integrated RNA In Situ Hybridization and Immunocytochemical Analysis

Circulating tumor cells (CTCs) are routinely identified as cytokeratin (CK)-positive, epithelial cell adhesion molecule (EpCAM)-positive, and CD45-negative and are enriched based on EpCAM. However, there are a number of methodological challenges regarding both isolation and characterization of these...

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Detalles Bibliográficos
Autores principales: Wu, Yongqi, Park, Kyoung-Joo Jenny, Deighan, Clayton, Amaya, Peter, Miller, Brandon, Pan, Quintin, Zborowski, Maciej, Lustberg, Maryam, Chalmers, Jeffery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099140/
https://www.ncbi.nlm.nih.gov/pubmed/27878106
http://dx.doi.org/10.3389/fonc.2016.00234