Tau Structures

Tau is a microtubule-associated protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity. In this review, we focus on the primary, secondary, tertiary, and quaternary tau structures. We describe the structure of tau from its specific residues until it...

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Detalles Bibliográficos
Autores principales: Avila, Jesus, Jiménez, Juan S., Sayas, Carmen L., Bolós, Marta, Zabala, Juan C., Rivas, Germán, Hernández, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099159/
https://www.ncbi.nlm.nih.gov/pubmed/27877124
http://dx.doi.org/10.3389/fnagi.2016.00262
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author Avila, Jesus
Jiménez, Juan S.
Sayas, Carmen L.
Bolós, Marta
Zabala, Juan C.
Rivas, Germán
Hernández, Felix
author_facet Avila, Jesus
Jiménez, Juan S.
Sayas, Carmen L.
Bolós, Marta
Zabala, Juan C.
Rivas, Germán
Hernández, Felix
author_sort Avila, Jesus
collection PubMed
description Tau is a microtubule-associated protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity. In this review, we focus on the primary, secondary, tertiary, and quaternary tau structures. We describe the structure of tau from its specific residues until its conformation in dimers, oligomers, and larger polymers in physiological and pathological situations.
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spelling pubmed-50991592016-11-22 Tau Structures Avila, Jesus Jiménez, Juan S. Sayas, Carmen L. Bolós, Marta Zabala, Juan C. Rivas, Germán Hernández, Felix Front Aging Neurosci Neuroscience Tau is a microtubule-associated protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity. In this review, we focus on the primary, secondary, tertiary, and quaternary tau structures. We describe the structure of tau from its specific residues until its conformation in dimers, oligomers, and larger polymers in physiological and pathological situations. Frontiers Media S.A. 2016-11-08 /pmc/articles/PMC5099159/ /pubmed/27877124 http://dx.doi.org/10.3389/fnagi.2016.00262 Text en Copyright © 2016 Avila, Jiménez, Sayas, Bolós, Zabala, Rivas and Hernández. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Avila, Jesus
Jiménez, Juan S.
Sayas, Carmen L.
Bolós, Marta
Zabala, Juan C.
Rivas, Germán
Hernández, Felix
Tau Structures
title Tau Structures
title_full Tau Structures
title_fullStr Tau Structures
title_full_unstemmed Tau Structures
title_short Tau Structures
title_sort tau structures
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099159/
https://www.ncbi.nlm.nih.gov/pubmed/27877124
http://dx.doi.org/10.3389/fnagi.2016.00262
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AT jimenezjuans taustructures
AT sayascarmenl taustructures
AT bolosmarta taustructures
AT zabalajuanc taustructures
AT rivasgerman taustructures
AT hernandezfelix taustructures

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