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Comparison of adding tocilizumab to methotrexate with switching to tocilizumab in patients with rheumatoid arthritis with inadequate response to methotrexate: 52-week results from a prospective, randomised, controlled study (SURPRISE study)
OBJECTIVE: To compare the efficacy and safety between tocilizumab added to methotrexate and tocilizumab switched from methotrexate in patients with active rheumatoid arthritis (RA). METHODS: This is a 2-year randomised, controlled study. RA patients with moderate or high disease activity despite met...
Autores principales: | Kaneko, Yuko, Atsumi, Tatsuya, Tanaka, Yoshiya, Inoo, Masayuki, Kobayashi-Haraoka, Hitomi, Amano, Koichi, Miyata, Masayuki, Murakawa, Yohko, Yasuoka, Hidekata, Hirata, Shintaro, Nagasawa, Hayato, Tanaka, Eiichi, Miyasaka, Nobuyuki, Yamanaka, Hisashi, Yamamoto, Kazuhiko, Takeuchi, Tsutomu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099201/ https://www.ncbi.nlm.nih.gov/pubmed/26733110 http://dx.doi.org/10.1136/annrheumdis-2015-208426 |
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