Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes

OBJECTIVES: Increasing evidence suggests an epigenetic contribution to the pathogenesis of autoimmune diseases, including primary Sjögren's Syndrome (pSS). The aim of this study was to investigate the role of DNA methylation in pSS by analysing multiple tissues from patients and controls. METHO...

Descripción completa

Detalles Bibliográficos
Autores principales: Imgenberg-Kreuz, Juliana, Sandling, Johanna K, Almlöf, Jonas Carlsson, Nordlund, Jessica, Signér, Linnea, Norheim, Katrine Braekke, Omdal, Roald, Rönnblom, Lars, Eloranta, Maija-Leena, Syvänen, Ann-Christine, Nordmark, Gunnel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099203/
https://www.ncbi.nlm.nih.gov/pubmed/26857698
http://dx.doi.org/10.1136/annrheumdis-2015-208659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099203/
https://www.ncbi.nlm.nih.gov/pubmed/26857698
http://dx.doi.org/10.1136/annrheumdis-2015-208659

Ejemplares similares