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Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes
OBJECTIVES: Increasing evidence suggests an epigenetic contribution to the pathogenesis of autoimmune diseases, including primary Sjögren's Syndrome (pSS). The aim of this study was to investigate the role of DNA methylation in pSS by analysing multiple tissues from patients and controls. METHO...
Autores principales: | Imgenberg-Kreuz, Juliana, Sandling, Johanna K, Almlöf, Jonas Carlsson, Nordlund, Jessica, Signér, Linnea, Norheim, Katrine Braekke, Omdal, Roald, Rönnblom, Lars, Eloranta, Maija-Leena, Syvänen, Ann-Christine, Nordmark, Gunnel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099203/ https://www.ncbi.nlm.nih.gov/pubmed/26857698 http://dx.doi.org/10.1136/annrheumdis-2015-208659 |
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