Cargando…

Targeting nitrative stress for attenuating cisplatin-induced downregulation of cochlear LIM domain only 4 and ototoxicity

Cisplatin-induced ototoxicity remains a primary dose-limiting adverse effect of this highly effective anticancer drug. The clinical utility of cisplatin could be enhanced if the signaling pathways that regulate the toxic side-effects are delineated. In previous studies, we reported cisplatin-induced...

Descripción completa

Detalles Bibliográficos
Autores principales: Jamesdaniel, Samson, Rathinam, Rajamani, Neumann, William L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099269/
https://www.ncbi.nlm.nih.gov/pubmed/27821327
http://dx.doi.org/10.1016/j.redox.2016.10.016