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Targeting nitrative stress for attenuating cisplatin-induced downregulation of cochlear LIM domain only 4 and ototoxicity

Cisplatin-induced ototoxicity remains a primary dose-limiting adverse effect of this highly effective anticancer drug. The clinical utility of cisplatin could be enhanced if the signaling pathways that regulate the toxic side-effects are delineated. In previous studies, we reported cisplatin-induced...

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Detalles Bibliográficos
Autores principales:	Jamesdaniel, Samson, Rathinam, Rajamani, Neumann, William L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099269/ https://www.ncbi.nlm.nih.gov/pubmed/27821327 http://dx.doi.org/10.1016/j.redox.2016.10.016

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