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Effects of transgenic methionine sulfoxide reductase A (MsrA) expression on lifespan and age-dependent changes in metabolic function in mice

Mechanisms that preserve and maintain the cellular proteome are associated with long life and healthy aging. Oxidative damage is a significant contributor to perturbation of proteostasis and is dealt with by the cell through regulation of antioxidants, protein degradation, and repair of oxidized ami...

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Detalles Bibliográficos
Autores principales:	Salmon, Adam B., Kim, Geumsoo, Liu, Chengyu, Wren, Jonathan D., Georgescu, Constantin, Richardson, Arlan, Levine, Rodney L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099276/ https://www.ncbi.nlm.nih.gov/pubmed/27821326 http://dx.doi.org/10.1016/j.redox.2016.10.012

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