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Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts
The overall decrease in proteolytic activity in aging can promote and accelerate protein accumulation and metabolic disturbances. To specifically analyze changes in macroautophagy (MA) we quantified different autophagy-related proteins (ATGs) in young, adult and old murine tissue as well as in young...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099282/ https://www.ncbi.nlm.nih.gov/pubmed/27825071 http://dx.doi.org/10.1016/j.redox.2016.10.015 |