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Mechanisms of aging-related proteinopathies in Caenorhabditis elegans

Aging is the most important risk factor for human neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. Pathologically, these diseases are characterized by the deposition of specific protein aggregates in neurons and glia, representing the impairment of neuronal proteost...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Kyu, Kim, Tae Ho, Lee, Seung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099420/
https://www.ncbi.nlm.nih.gov/pubmed/27713398
http://dx.doi.org/10.1038/emm.2016.109