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Effect of fermented red ginseng on cytochrome P450 and P‐glycoprotein activity in healthy subjects, as evaluated using the cocktail approach

AIMS: We assessed the drug interaction profile of fermented red ginseng with respect to the activity of major cytochrome (CYP) P450 enzymes and of a drug transporter protein, P‐glycoprotein (P‐gp), in healthy volunteers. METHODS: This study was an open‐label crossover study. The CYP probe cocktail d...

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Detalles Bibliográficos
Autores principales: Kim, Min‐Gul, Kim, Yunjeong, Jeon, Ji‐Young, Kim, Dal‐Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099554/
https://www.ncbi.nlm.nih.gov/pubmed/27495955
http://dx.doi.org/10.1111/bcp.13080