Detailed Analysis of Protein Topology of Extracellular Vesicles–Evidence of Unconventional Membrane Protein Orientation

Extracellular vesicles (EVs) are important mediators of intercellular communication that change the recipient cell by shuttling lipids, RNA, or protein cargo between cells. Here, we investigate the topology of the protein cargo found in EVs, as this topology can fundamentally influence the biologica...

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Detalles Bibliográficos
Autores principales: Cvjetkovic, Aleksander, Jang, Su Chul, Konečná, Barbora, Höög, Johanna L., Sihlbom, Carina, Lässer, Cecilia, Lötvall, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099568/
https://www.ncbi.nlm.nih.gov/pubmed/27821849
http://dx.doi.org/10.1038/srep36338

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