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Enterogenous bacterial glycolipids are required for the generation of natural killer T cells mediated liver injury

Glycolipids are potent activator of natural killer T (NKT) cells. The relationship between NKT cells and intestinal bacterial glycolipids in liver disorders remained unclear. We found that, in sharp contrast to specific pathogen-free (SPF) mice, germ-free (GF) mice are resistant to Concanavalin A (C...

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Detalles Bibliográficos
Autores principales: Wei, Yingfeng, Zeng, Benhua, Chen, Jianing, Cui, Guangying, Lu, Chong, Wu, Wei, Yang, Jiezuan, Wei, Hong, Xue, Rufeng, Bai, Li, Chen, Zhi, Li, Lanjuan, Iwabuchi, Kazuya, Uede, Toshimitsu, Van Kaer, Luc, Diao, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099575/
https://www.ncbi.nlm.nih.gov/pubmed/27821872
http://dx.doi.org/10.1038/srep36365