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Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia
AIM: To summarize the reported Middle East respiratory syndrome-coronavirus (MERS-CoV) cases, the associated clinical presentations and the outcomes. METHODS: We searched the Saudi Ministry of Health website, the World Health Organization website, and the Flutracker website. We also searched MEDLINE...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099592/ https://www.ncbi.nlm.nih.gov/pubmed/27872828 http://dx.doi.org/10.5409/wjcp.v5.i4.391 |
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author | Al-Tawfiq, Jaffar A Kattan, Rana F Memish, Ziad A |
author_facet | Al-Tawfiq, Jaffar A Kattan, Rana F Memish, Ziad A |
author_sort | Al-Tawfiq, Jaffar A |
collection | PubMed |
description | AIM: To summarize the reported Middle East respiratory syndrome-coronavirus (MERS-CoV) cases, the associated clinical presentations and the outcomes. METHODS: We searched the Saudi Ministry of Health website, the World Health Organization website, and the Flutracker website. We also searched MEDLINE and PubMed for the keywords: Middle East respiratory syndrome-coronavirus, MERS-CoV in combination with pediatric, children, childhood, infancy and pregnancy from the initial discovery of the virus in 2012 to 2016. The retrieved articles were also read to further find other articles. Relevant data were placed into an excel sheet and analyzed accordingly. Descriptive analytic statistics were used in the final analysis as deemed necessary. RESULTS: From June 2012 to April 19, 2016, there were a total of 31 pediatric MERS-CoV cases. Of these cases 13 (42%) were asymptomatic and the male to female ratio was 1.7:1. The mean age of patients was 9.8 ± 5.4 years. Twenty-five (80.6%) of the cases were reported from the Kingdom of Saudi Arabia. The most common source of infection was household contact (10 of 15 with reported source) and 5 patients acquired infection within a health care facility. Using real time reverse transcriptase polymerase chain reaction of pediatric patients revealed that 9 out of 552 (1.6%) was positive in the Kingdom of Saudi Arabia. CONCLUSION: Utilizing serology for MERS-CoV infection in Jordan and Saudi Arabia did not reveal any positive patients. Thus, the number of the pediatric MERS-CoV is low; the exact reason for the low prevalence of the disease in children is not known. |
format | Online Article Text |
id | pubmed-5099592 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-50995922016-11-21 Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia Al-Tawfiq, Jaffar A Kattan, Rana F Memish, Ziad A World J Clin Pediatr Systematic Reviews AIM: To summarize the reported Middle East respiratory syndrome-coronavirus (MERS-CoV) cases, the associated clinical presentations and the outcomes. METHODS: We searched the Saudi Ministry of Health website, the World Health Organization website, and the Flutracker website. We also searched MEDLINE and PubMed for the keywords: Middle East respiratory syndrome-coronavirus, MERS-CoV in combination with pediatric, children, childhood, infancy and pregnancy from the initial discovery of the virus in 2012 to 2016. The retrieved articles were also read to further find other articles. Relevant data were placed into an excel sheet and analyzed accordingly. Descriptive analytic statistics were used in the final analysis as deemed necessary. RESULTS: From June 2012 to April 19, 2016, there were a total of 31 pediatric MERS-CoV cases. Of these cases 13 (42%) were asymptomatic and the male to female ratio was 1.7:1. The mean age of patients was 9.8 ± 5.4 years. Twenty-five (80.6%) of the cases were reported from the Kingdom of Saudi Arabia. The most common source of infection was household contact (10 of 15 with reported source) and 5 patients acquired infection within a health care facility. Using real time reverse transcriptase polymerase chain reaction of pediatric patients revealed that 9 out of 552 (1.6%) was positive in the Kingdom of Saudi Arabia. CONCLUSION: Utilizing serology for MERS-CoV infection in Jordan and Saudi Arabia did not reveal any positive patients. Thus, the number of the pediatric MERS-CoV is low; the exact reason for the low prevalence of the disease in children is not known. Baishideng Publishing Group Inc 2016-11-08 /pmc/articles/PMC5099592/ /pubmed/27872828 http://dx.doi.org/10.5409/wjcp.v5.i4.391 Text en ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Systematic Reviews Al-Tawfiq, Jaffar A Kattan, Rana F Memish, Ziad A Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia |
title | Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia |
title_full | Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia |
title_fullStr | Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia |
title_full_unstemmed | Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia |
title_short | Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia |
title_sort | middle east respiratory syndrome coronavirus disease is rare in children: an update from saudi arabia |
topic | Systematic Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099592/ https://www.ncbi.nlm.nih.gov/pubmed/27872828 http://dx.doi.org/10.5409/wjcp.v5.i4.391 |
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