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Nitidine chloride prevents OVX-induced bone loss via suppressing NFATc1-mediated osteoclast differentiation
Nitidine chloride (NC), a bioactive alkaloid isolated from Zanthoxylum nitidum, has been used as a herbal ingredient in toothpaste that prevents cavities for decades. It also displays potential antitumor and anti-inflammation properties. However, its anticatabolic effect on bone is not known. We inv...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099608/ https://www.ncbi.nlm.nih.gov/pubmed/27821837 http://dx.doi.org/10.1038/srep36662 |