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Ascorbic acid oxidation of thiol groups from dithiotreitol is mediated by its conversion to dehydroascorbic acid

The aim of the present study was to investigate whether the in vitro pro-oxidant effect of ascorbic acid towards thiol groups could be mediated by free radicals formed during its auto-oxidation and/or by a direct oxidation of -SH groups by its oxidized form (dehydroascorbic acid). This hypothesis wa...

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Detalles Bibliográficos
Autores principales: Barbosa, Nilda B.V., Lissner, Leandro A., Klimaczewski, Cláudia V., Colpo, Elisangela, Rocha, Joao B.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099875/
https://www.ncbi.nlm.nih.gov/pubmed/27847448