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Structural changes induced by acidic pH in human apolipoprotein B-100

Acidification in the endosome causes lipoprotein release by promoting a conformational change in the LDLR allowing its recycling and degradation of LDL. Notwithstanding conformational changes occurring in the LDLR have expanded considerably, structural changes occurring in LDL particles have not bee...

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Detalles Bibliográficos
Autores principales:	Fernández-Higuero, José A., Benito-Vicente, Asier, Etxebarria, Aitor, Milicua, José Carlos G., Ostolaza, Helena, Arrondo, José L. R., Martín, Cesar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099883/ https://www.ncbi.nlm.nih.gov/pubmed/27824107 http://dx.doi.org/10.1038/srep36324

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