LRBA is Essential for Allogeneic Responses in Bone Marrow Transplantation

The PH-BEACH-WD40 (PBW) protein family members play a role in coordinating receptor signaling and intracellular vesicle trafficking. LPS-Responsive-Beige-like Anchor (LRBA) is a PBW protein whose immune function remains elusive. Here we show that LRBA-null mice are viable, but exhibit compromised re...

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Detalles Bibliográficos
Autores principales: Park, Mi Young, Sudan, Raki, Srivastava, Neetu, Neelam, Sudha, Youngs, Christie, Wang, Jia-Wang, Engelman, Robert W., Kerr, William G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099895/
https://www.ncbi.nlm.nih.gov/pubmed/27824136
http://dx.doi.org/10.1038/srep36568

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