Cargando…

Real time monitoring of membrane GPCR reconstitution by plasmon waveguide resonance: on the role of lipids

G-protein coupled receptors (GPCRs) are important therapeutic targets since more than 40% of the drugs on the market exert their action through these proteins. To decipher the molecular mechanisms of activation and signaling, GPCRs often need to be isolated and reconstituted from a detergent-solubil...

Descripción completa

Detalles Bibliográficos
Autores principales: Calmet, Pierre, De Maria, Monica, Harté, Etienne, Lamb, Daniel, Serrano-Vega, Maria, Jazayeri, Ali, Tschammer, Nuska, Alves, Isabel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099921/
https://www.ncbi.nlm.nih.gov/pubmed/27824122
http://dx.doi.org/10.1038/srep36181