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Real time monitoring of membrane GPCR reconstitution by plasmon waveguide resonance: on the role of lipids
G-protein coupled receptors (GPCRs) are important therapeutic targets since more than 40% of the drugs on the market exert their action through these proteins. To decipher the molecular mechanisms of activation and signaling, GPCRs often need to be isolated and reconstituted from a detergent-solubil...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099921/ https://www.ncbi.nlm.nih.gov/pubmed/27824122 http://dx.doi.org/10.1038/srep36181 |